Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T59445
|
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| Former ID |
TTDR00879
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| Target Name |
Sorbitoldehydrogenase
|
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| Gene Name |
SORD
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| Synonyms |
L-iditol2-dehydrogenase; SDH; SORD
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| Target Type |
Research
|
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| Function |
Convertssorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm.
|
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| BioChemical Class |
Short-chain dehydrogenases reductases
|
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| UniProt ID | |||||
| EC Number |
EC 1.1.1.14
|
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| Sequence |
MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF
IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCG AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP |
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| Pathways | |||||
| BioCyc Pathway | Sorbitol degradation I | ||||
| KEGG Pathway | Pentose and glucuronate interconversions | ||||
| Fructose and mannose metabolism | |||||
| Metabolic pathways | |||||
| NetPath Pathway | TSH Signaling Pathway | ||||
| PathWhiz Pathway | Fructose and Mannose Degradation | ||||
| WikiPathways | Polyol Pathway | ||||
| References | |||||
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