Target Information

Target General Infomation
Target ID
T70201
Former ID
TTDI02081
Target Name
Glioma pathogenesis-related protein 1
Gene Name
GLIPR1
Synonyms
GliPR 1; Protein RTVP1; GLIPR1
Target Type
Clinical Trial
Disease Prostate cancer [ICD9: 185; ICD10: C61]
BioChemical Class
Cysteine-rich secretory protein
UniProt ID
P48060
Sequence
MRVTLATIAWMVSFVSNYSHTANILPDIENEDFIKDCVRIHNKFRSEVKPTASDMLYMTW
DPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLGENIWTGSVPIFSVSSAITNWYDE
IQDYDFKTRICKKVCGHYTQVVWADSYKVGCAVQFCPKVSGFDALSNGAHFICNYGPGGN
YPTWPYKRGATCSACPNNDKCLDNLCVNRQRDQVKRYYSVVYPGWPIYPRNRYTSLFLIV
NSVILILSVIITILVQHKYPNLVLLD
Drugs and Mode of Action
Drug(s) AdRTVP-1 Drug Info Phase 1 Prostate cancer [528044]
Modulator AdRTVP-1 Drug Info [528044]
Target Expression Profile (TEP) and Drug Resistance Mutation (DRM)
TEP EXP Info
Pathways
Reactome PPARA activates gene expression
WikiPathways Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
References
Ref 528044Adenoviral vector-mediated RTVP-1 gene-modified tumor cell-based vaccine suppresses the development of experimental prostate cancer. Cancer Gene Ther. 2006 Jul;13(7):658-63. Epub 2006 Feb 17.
Ref 528044Adenoviral vector-mediated RTVP-1 gene-modified tumor cell-based vaccine suppresses the development of experimental prostate cancer. Cancer Gene Ther. 2006 Jul;13(7):658-63. Epub 2006 Feb 17.

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