Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T75655
|
||||
| Former ID |
TTDR00441
|
||||
| Target Name |
Apolipoprotein A-II
|
||||
| Gene Name |
APOA2
|
||||
| Synonyms |
Apo-AII; ApoA-II; APOA2
|
||||
| Target Type |
Research
|
||||
| Function |
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
|
||||
| BioChemical Class |
Apolipoprotein
|
||||
| UniProt ID | |||||
| Sequence |
MKLLAATVLLLTICSLEGALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAE
AKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPATQ |
||||
| Inhibitor | B-Octylglucoside | Drug Info | [1] | ||
| Pathways | |||||
| KEGG Pathway | PPAR signaling pathway | ||||
| Reactome | Chylomicron-mediated lipid transport | ||||
| PPARA activates gene expression | |||||
| Retinoid metabolism and transport | |||||
| WikiPathways | Complement and Coagulation Cascades | ||||
| Statin Pathway | |||||
| Nuclear Receptors Meta-Pathway | |||||
| PPAR Alpha Pathway | |||||
| Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | |||||
| Visual phototransduction | |||||
| Lipid digestion, mobilization, and transport | |||||
| References | |||||
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.