Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T86717
|
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| Former ID |
TTDR00762
|
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| Target Name |
3-dehydroquinate synthase
|
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| Gene Name |
aroB
|
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| Synonyms |
AROB; Dehydroquinatesynthase; aroB
|
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| Target Type |
Research
|
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| BioChemical Class |
Carbon-oxygen lyases
|
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| UniProt ID | |||||
| EC Number |
EC 4.2.3.4
|
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| Sequence |
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQA
GVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQR GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELAS GLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRA GLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQ SA |
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| Inhibitor | Carbaphosphonate | Drug Info | [1] | ||
| Nicotinamide-Adenine-Dinucleotide | Drug Info | [1] | |||
| Pathways | |||||
| PANTHER Pathway | Chorismate biosynthesis | ||||
| References | |||||
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | ||||
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