Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T88057
|
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| Former ID |
TTDR00133
|
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| Target Name |
L-lactate dehydrogenase
|
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| Synonyms |
LDH; LDH1; Lactate dehydrogenase
|
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| Target Type |
Research
|
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| BioChemical Class |
Short-chain dehydrogenases reductases
|
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| UniProt ID | |||||
| EC Number |
EC 1.1.1.27
|
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| Sequence |
MTGTVSRRKKIAMIGSGMIGGTMGYLCVLRELADVVLFDVVTGMPEGKALDDSQATSIAD
TNVSVTSANQYEKIAGSDVVIITAGLTKVPGKSDKEWSRNDLLPFNAKIIREVAQGVKKY CPLAFVIVVTNPLDCMVKCFHEASGLPKNMVCGMANVLDSARFRRFIADQLEISPRDIQA TVIGTHGDHMLPLARYVTVSGFPLREFIKKGKMTEAKLAEIVERTKKAGGEIVRLLGQGS AYYAPALSAITMAQAFLKDEKRVLPCSVYCQGEYGLHDMFIGLPAVIGGGGIEQVIELEL THEEQECFRKSVDDVVELNKSLAALG |
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| Inhibitor | 3,7-DIHYDROXYNAPHTHALENE-2-CARBOXYLIC ACID | Drug Info | [1] | ||
| 3-Hydroxyisoxazole-4-Carboxylic Acid | Drug Info | [2] | |||
| 4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid | Drug Info | [2] | |||
| 4-Hydroxy-1,2,5-Thiadiazole-3-Carboxylic Acid | Drug Info | [2] | |||
| Naphthalene-2,6-disulfonic acid | Drug Info | [3] | |||
| Nicotinamide-Adenine-Dinucleotide | Drug Info | [2] | |||
| Oxamic Acid | Drug Info | [2] | |||
| References | |||||
| REF 1 | DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-4. Nucleic Acids Res. 2011 January | ||||
| REF 2 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | ||||
| REF 3 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | ||||
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