Target Information

Target General Infomation
Target ID
T88057
Former ID
TTDR00133
Target Name
L-lactate dehydrogenase
Synonyms
LDH; LDH1; Lactate dehydrogenase
Target Type
Research
BioChemical Class
Short-chain dehydrogenases reductases
UniProt ID
Q27797
EC Number
EC 1.1.1.27
Sequence
MTGTVSRRKKIAMIGSGMIGGTMGYLCVLRELADVVLFDVVTGMPEGKALDDSQATSIAD
TNVSVTSANQYEKIAGSDVVIITAGLTKVPGKSDKEWSRNDLLPFNAKIIREVAQGVKKY
CPLAFVIVVTNPLDCMVKCFHEASGLPKNMVCGMANVLDSARFRRFIADQLEISPRDIQA
TVIGTHGDHMLPLARYVTVSGFPLREFIKKGKMTEAKLAEIVERTKKAGGEIVRLLGQGS
AYYAPALSAITMAQAFLKDEKRVLPCSVYCQGEYGLHDMFIGLPAVIGGGGIEQVIELEL
THEEQECFRKSVDDVVELNKSLAALG
Inhibitor 3,7-DIHYDROXYNAPHTHALENE-2-CARBOXYLIC ACID Drug Info [551391]
3-Hydroxyisoxazole-4-Carboxylic Acid Drug Info [551393]
4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid Drug Info [551393]
4-Hydroxy-1,2,5-Thiadiazole-3-Carboxylic Acid Drug Info [551393]
Naphthalene-2,6-disulfonic acid Drug Info [551374]
Nicotinamide-Adenine-Dinucleotide Drug Info [551393]
Oxamic Acid Drug Info [551393]
References
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
Ref 551391DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-4. Nucleic Acids Res. 2011 January
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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