Drug General Information
Drug ID	D00DDJ
Former ID	DNC007938
Drug Name	Adamantan-1-yl-piperazin-1-yl-methanone
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528722]
Structure		Download 2D MOL 3D MOL
Formula	C15H24N2O
Canonical SMILES	C1CN(CCN1)C(=O)C23CC4CC(C2)CC(C4)C3
InChI	1S/C15H24N2O/c18-14(17-3-1-16-2-4-17)15-8-11-5-12(9-15)7-13(6-11)10-15/h11-13,16H,1-10H2
InChIKey	XAFSAELWLMDLKL-UHFFFAOYSA-N
PubChem Compound ID	17233943
Target and Pathway
Target(s)	Corticosteroid 11-beta-dehydrogenase, isozyme 1	Target Info	Inhibitor	[528722]
KEGG Pathway	Steroid hormone biosynthesis
	Metabolism of xenobiotics by cytochrome P450
	Metabolic pathways
	Chemical carcinogenesis
NetPath Pathway	IL1 Signaling Pathway
	FSH Signaling Pathway
PathWhiz Pathway	Steroidogenesis
Reactome	Glucocorticoid biosynthesis
WikiPathways	Prostaglandin Synthesis and Regulation
	Metabolism of steroid hormones and vitamin D
	Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 528722	Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. Epub 2007 Feb 25.Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.
Ref 528722	Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. Epub 2007 Feb 25.Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.

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