Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00FJC
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| Former ID |
DIB001924
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| Drug Name |
Nuvanil
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| Synonyms |
NE-21610
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| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Discontinued in Phase 2 | [1] | ||
| Company |
Procter & Gamble Pharmaceuticals Inc
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
c1(c(ccc(c1)CNC(=O)CCCCCCC/C=C\CCCCCCCC)OCCN)OC
|
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| CAS Number |
CAS 118090-17-8
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| Target and Pathway | |||||
| Target(s) | Vanilloid receptor 1 | Target Info | Agonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Inflammatory mediator regulation of TRP channels | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
| Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
| Reactome | TRP channels | ||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003434) | ||||
| REF 2 | TRPV1: ON THE ROAD TO PAIN RELIEF. Curr Mol Pharmacol. 2008 November; 1(3): 255-269. | ||||
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