Drug Information

Drug General Information
Drug ID
D00ICA
Former ID
DIB018846
Drug Name
AMP-PNP
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539585]
Structure
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2D MOL

3D MOL
Formula
C10H17N6O12P3
InChI
InChI=1S/C10H17N6O12P3/c11-8-5-9(13-2-12-8)16(3-14-5)10-7(18)6(17)4(27-10)1-26-31(24,25)28-30(22,23)15-29(19,20)21/h2-4,6-7,10,17-18H,1H2,(H,24,25)(H2,11,12,13)(H4,15,19,20,21,22,23)/t4-,6-,7-,10-/m1/s1
InChIKey
PVKSNHVPLWYQGJ-KQYNXXCUSA-N
PubChem Compound ID
33113
PubChem Substance ID
583913, 584117, 584243, 584509, 584510, 584597, 584642, 584903, 584914, 585719, 819402, 820983, 822417, 822420, 822555, 822615, 822674, 822729, 823068, 823069, 823071, 823147, 823562, 825190, 825870, 826170, 826819, 827599, 827601, 827758, 827760, 827764, 827772, 828281, 828283, 829378, 829584, 830048, 830394, 830406, 830899, 831291, 833416, 833811, 834459, 834825, 835942, 835983, 837044, 837385
Target and Pathway
Target(s) TRPM4 Target Info Inhibitor (gating inhibitor) [526954]
References
Ref 539585(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2456).
Ref 526954Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b. Pflugers Arch. 2004 Apr;448(1):70-5. Epub 2004 Jan 31.

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