Drug Information

Drug General Information
Drug ID
D00ICM
Former ID
DIB006630
Drug Name
NALTIAZEM HYDROCHLORIDE
Synonyms
Ro-23-6152; Ro-23-6152/001; (+)-cis-3-Acetoxy-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-2,3,4,5-tetrahydronaphtho[1,2-b][1,4]thiazepin-4-one hydrochloride
Drug Type
Small molecular drug
Indication Angina pectoris [ICD9: 413; ICD10:I20] Terminated [544616]
Structure
Download
2D MOL

3D MOL
Formula
C26H29ClN2O4S
Canonical SMILES
CC(=O)OC1C(SC2=C(C=CC3=CC=CC=C32)N(C1=O)CCN(C)C)C4=CC=C<br />(C=C4)OC.Cl
InChI
1S/C26H28N2O4S.ClH/c1-17(29)32-23-24(19-9-12-20(31-4)13-10-19)33-25-21-8-6-5-7-18(21)11-14-22(25)28(26(23)30)16-15-27(2)3;/h5-14,23-24H,15-16H2,1-4H3;1H/t23-,24+;/m1./s1
InChIKey
SFTBZKFGODNAKF-ITNPDYSASA-N
PubChem Compound ID
130121
PubChem Substance ID
16419609, 29308793, 75576200, 104372050, 135085073, 198942427, 233032228
Target and Pathway
Target(s) Calcium channel Target Info Blocker [529043], [551871]
References
Ref 544616Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000300)
Ref 529043Assessment of hyperglycemia after calcium channel blocker overdoses involving diltiazem or verapamil. Crit Care Med. 2007 Sep;35(9):2071-5.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.