Drug Information

Drug General Information
Drug ID
D00JMA
Former ID
DIB019168
Drug Name
compound 1
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526092], [541669]
Structure
Download
2D MOL
Formula
C16H14N2O2
InChI
InChI=1S/C16H14N2O2/c19-15-17(11-13-7-3-1-4-8-13)16(20)18(15)12-14-9-5-2-6-10-14/h1-10H,11-12H2
InChIKey
PGIXYPNBNAOYHW-UHFFFAOYSA-N
PubChem Compound ID
10038543
PubChem Substance ID
15021140, 22463247, 44155602, 76046544, 103227576, 103997827, 126559159, 134351780, 178103156
Target and Pathway
Target(s) Cathepsin G Target Info Inhibitor [526092]
KEGG Pathway Neuroactive ligand-receptor interaction
Lysosome
Renin-angiotensin system
Amoebiasis
Systemic lupus erythematosus
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
WikiPathways ACE Inhibitor Pathway
Regulation of Insulin-like Growth Factor (IGF) Transport and Uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
References
Ref 526092Bioorg Med Chem Lett. 2001 Jul 9;11(13):1691-4.Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones.
Ref 541669(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6542).
Ref 526092Bioorg Med Chem Lett. 2001 Jul 9;11(13):1691-4.Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones.

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