Drug Information
Drug General Information | |||||
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Drug ID |
D00MAN
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Former ID |
DIB009942
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Drug Name |
GRC-6211
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Synonyms |
GRC-6127; TRPV1 antagonists (asthma), Glenmark/Lilly; TRPV1 antagonists (incontinence), Glenmark/Lilly; TRPV1 antagonists (pain), Glenmark/Lilly; Transient receptor potential vanilloid sub-family 1 (pain), Glenmark/ Lilly; Vanilloid receptor VR1 antagonists (incontinence/pain/asthma), Glenmark/Lilly
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Drug Type |
Small molecular drug
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Indication | Asthma [ICD10:J45] | Phase 1 | [548350] | ||
Company |
Glenmark Pharmaceuticals Ltd
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Structure |
Download2D MOL |
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Formula |
C13H11NO5
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Canonical SMILES |
CCN1C=C(C(=O)C2=CC3=C(C=C21)OCO3)C(=O)O
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InChI |
1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)
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InChIKey |
KYGZCKSPAKDVKC-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
13517, 409113, 590678, 597741, 855760, 5203902, 7849360, 7889637, 8149801, 8152840, 10321595, 11111565, 11111566, 11335834, 11361073, 11364291, 11366853, 11369415, 11372678, 11373764, 11377577, 11462045, 11466221, 11467341, 11484602, 11485802, 11488749, 11491305, 11491888, 11495211, 15197066, 17405510, 24278604, 25621581, 26612267, 26679848, 26747409, 26747410, 29223717, 47216777, 47588997, 47588998, 47736482, 47810754, 47810755, 47810756, 48035124, 48259230, 48414265, 48416363
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Target and Pathway | |||||
Target(s) | Vanilloid receptor 1 | Target Info | Antagonist | [529807] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
Reactome | TRP channels | ||||
References |
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