Drug Information
Drug General Information | |||||
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Drug ID |
D00NXT
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Former ID |
DNCL003798
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Drug Name |
Xmab 5871
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Synonyms |
XmAb 5871 (TN)
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Indication | Autoimmune diabetes [ICD10:E08-E13] | Phase 2 | [549317] | ||
Company |
Amgen; Xencor
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Target and Pathway | |||||
Target(s) | CD32b | Target Info | Modulator | [531971] | |
B-lymphocyte antigen CD19 | Target Info | Modulator | |||
NetPath Pathway | Leptin Signaling PathwayNetPath_19:IL-7 Signaling Pathway | ||||
PANTHER Pathway | B cell activation | ||||
Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
BCR signaling pathwaybcr_5pathway:BCR signaling pathway | |||||
Reactome | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellR-HSA-1257604:PIP3 activates AKT signaling | ||||
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | |||||
Constitutive Signaling by Aberrant PI3K in Cancer | |||||
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | |||||
References |
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