Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00SHX
|
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| Former ID |
DNC008253
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| Drug Name |
1-[2-(2,4,6-trimethyl-phenyl)-ethyl]-pyrrolidine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C15H23N
|
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| Canonical SMILES |
CC1=CC(=C(C(=C1)C)CCN2CCCC2)C
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| InChI |
1S/C15H23N/c1-12-10-13(2)15(14(3)11-12)6-9-16-7-4-5-8-16/h10-11H,4-9H2,1-3H3
|
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| InChIKey |
IYOUBSBBWJSRIG-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2008 Jan 1;18(1):355-9. Epub 2007 Oct 24.In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series. | ||||
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