Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00TRF
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| Former ID |
DNC007393
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| Drug Name |
2-(benzyloxyamino)-N-hydroxyacetamide
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C9H12N2O3
|
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| Canonical SMILES |
C1=CC=C(C=C1)CONCC(=O)NO
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| InChI |
1S/C9H12N2O3/c12-9(11-13)6-10-14-7-8-4-2-1-3-5-8/h1-5,10,13H,6-7H2,(H,11,12)
|
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| InChIKey |
PMVJGZGFFBJYLQ-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase IX | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | ||||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | ||||
| Reactome | Regulation of gene expression by Hypoxia-inducible Factor | ||||
| Reversible hydration of carbon dioxide | |||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Reversible Hydration of Carbon Dioxide | |||||
| Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | |||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2007 Mar 15;15(6):2298-311. Epub 2007 Jan 19.Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I andII with sulfonylated hydroxamates. | ||||
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