Drug Information

Drug General Information
Drug ID
D00WVW
Former ID
DNAP001707
Drug Name
YM443
Synonyms
Acofide; Acotiamide
Drug Type
Small molecular drug
Indication Upper abdominal bloating; Early satiation associated with functional dyspepsia [ICD9: 536.8; ICD10:K30] Approved [551871]
Company
Astellas
Structure
Download
2D MOL

3D MOL
Formula
C21H30N4O5S
Canonical SMILES
CC(C)N(CCNC(=O)C1=CSC(=N1)NC(=O)C2=CC(=C(C=C2O)OC)OC)C(<br />C)C
InChI
1S/C21H30N4O5S/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26/h9-13,26H,7-8H2,1-6H3,(H,22,28)(H,23,24,27)
InChIKey
TWHZNAUBXFZMCA-UHFFFAOYSA-N
CAS Number
CAS 185106-16-5
PubChem Compound ID
5282338
PubChem Substance ID
7846941, 8617011, 15240378, 39315799, 57358620, 80913119, 96099914, 113856990, 127337692, 129323426, 135252372, 137248680, 144240151, 160692977, 162219968, 198979231, 223442498, 223662504, 227292955, 252434050
Target and Pathway
Target(s) Acetylcholinesterase Target Info Modulator [551871]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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