Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00YVR
|
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| Former ID |
DIB020599
|
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| Drug Name |
oleamide
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C18H35NO
|
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| InChI |
InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-
|
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| InChIKey |
FATBGEAMYMYZAF-KTKRTIGZSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
87668, 585266, 7887303, 10517713, 11038950, 11113753, 14848775, 26751932, 26751933, 26751934, 39316798, 47959446, 48334200, 48417534, 48420782, 49703514, 49846842, 49998733, 50104610, 53788812, 56365478, 57298450, 57358917, 57391339, 76732824, 87350517, 87574113, 91746390, 92309905, 93374599, 98458014, 99300819, 99302337, 103178862, 104046474, 113859930, 124886950, 126524367, 126688203, 134975607, 135626138, 135651530, 137019767, 142454778, 144207642, 144226852, 162174807, 162227355, 163414984, 163849314
|
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| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 7 receptor | Target Info | Modulator (allosteric modulator) | [2] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Calcium signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| Serotonergic synapse | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| PathWhiz Pathway | Excitatory Neural Signalling Through 5-HTR 7 and Serotonin | ||||
| Reactome | Serotonin receptors | ||||
| G alpha (s) signalling events | |||||
| WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | ||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 284). | ||||
| REF 2 | Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine7 receptors. Biochem Pharmacol. 1999 Dec 1;58(11):1807-13. | ||||
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