Drug Information

Drug General Information
Drug ID
D01FRF
Former ID
DNC012103
Drug Name
Trequinsin
Drug Type
Small molecular drug
Indication Discovery agent Terminated [544656]
Structure
Download
2D MOL

3D MOL
Formula
C24H27N3O3
Canonical SMILES
CC1=CC(=C(C(=C1)C)N=C2C=C3C4=CC(=C(C=C4CCN3C(=O)N2C)OC)<br />OC)C
InChI
1S/C24H27N3O3/c1-14-9-15(2)23(16(3)10-14)25-22-13-19-18-12-21(30-6)20(29-5)11-17(18)7-8-27(19)24(28)26(22)4/h9-13H,7-8H2,1-6H3
InChIKey
MCMSJVMUSBZUCN-UHFFFAOYSA-N
PubChem Compound ID
5537
Target and Pathway
Target(s) CGMP-specific 3',5'-cyclic phosphodiesterase Target Info Inhibitor [533047]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Reactome cGMP effects
References
Ref 544656Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000447)
Ref 533047J Med Chem. 1989 Jul;32(7):1450-7.Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.