Drug Information

Drug General Information
Drug ID
D01GUK
Former ID
DNC012225
Drug Name
Cyclopentyl-(9-phenyl-9H-purin-6-yl)-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529774]
Structure
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2D MOL

3D MOL
Formula
C16H17N5
Canonical SMILES
C1CCC(C1)NC2=NC=NC3=C2N=CN3C4=CC=CC=C4
InChI
1S/C16H17N5/c1-2-8-13(9-3-1)21-11-19-14-15(17-10-18-16(14)21)20-12-6-4-5-7-12/h1-3,8-12H,4-7H2,(H,17,18,20)
InChIKey
HMTXZOPPYXBLIU-UHFFFAOYSA-N
PubChem Compound ID
15693952
Target and Pathway
Target(s) Adenosine A1 receptor Target Info Inhibitor [529774]
KEGG Pathway cGMP-PKG signaling pathway
cAMP signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
Morphine addiction
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529774J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.
Ref 529774J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.

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