Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01GUS
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| Former ID |
DAP000960
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| Drug Name |
Udenafil
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| Synonyms |
Zydena; DA 8159; DA-8159; Zydena (TN); 3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzenesulfonamide; 5-(2-Propyloxy-5-(1-methyl-2-pyrollidinylethylamidosulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo(4,3-d)pyrimidine-7-one
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| Drug Type |
Small molecular drug
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| Indication | Erectile dysfunction [ICD9: 302.72, 607.84; ICD10:F52.2, N48.4] | Approved | [536361] | ||
| Therapeutic Class |
Vasodilator Agents
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| Company |
Dong-A Pharmaceutical
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| Structure |
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Download2D MOL |
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| Formula |
C25H36N6O4S
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| Canonical SMILES |
CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)NCCC4CCC<br />N4C)OCCC)C
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| InChI |
1S/C25H36N6O4S/c1-5-8-20-22-23(31(4)29-20)25(32)28-24(27-22)19-16-18(10-11-21(19)35-15-6-2)36(33,34)26-13-12-17-9-7-14-30(17)3/h10-11,16-17,26H,5-9,12-15H2,1-4H3,(H,27,28,32)
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| InChIKey |
IYFNEFQTYQPVOC-UHFFFAOYSA-N
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| CAS Number |
CAS 268203-93-6
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| PubChem Compound ID | |||||
| PubChem Substance ID |
12015432, 15181651, 16896098, 17194940, 43529893, 50430522, 57371963, 99443240, 99452560, 104178316, 114788102, 134224591, 134338234, 134340602, 135271929, 135626747, 137082780, 137237692, 138091955, 138937364, 141714788, 152041640, 160687015, 160967855, 163108842, 164235286, 164766037, 176251591, 196411563, 210275732, 210281393, 223922924, 226492530, 246737278
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| Target and Pathway | |||||
| Target(s) | CGMP-specific 3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [537372] | |
| KEGG Pathway | Purine metabolism | ||||
| cGMP-PKG signaling pathway | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Reactome | cGMP effects | ||||
| References | |||||
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