Drug Information
Drug General Information | |||||
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Drug ID |
D01JLO
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Former ID |
DIB010336
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Drug Name |
Tat-NR2B9c
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Synonyms |
NA-1; NA-1); PSD-95 inhibitor (stroke), NoNO/Arbor Vita; NMDAR NR2 domain-binding protein + HIV-1 Tat protein (Stroke), NoNO/Arbor Vita
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Company |
Nono inc
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Structure |
Download2D MOL |
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Target and Pathway | |||||
Target(s) | Presynaptic density protein 95 | Target Info | Inhibitor | [525512], [531828], [533640] | |
PANTHER Pathway | Huntington disease | ||||
Pathway Interaction Database | ErbB4 signaling events | ||||
References | |||||
Ref 525512 | Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science. 1999 Jun 11;284(5421):1845-8. | ||||
Ref 531828 | Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature. 2012 Feb 29;483(7388):213-7. | ||||
Ref 533640 | Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science. 1995 Sep 22;269(5231):1737-40. | ||||
Ref 525512 | Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science. 1999 Jun 11;284(5421):1845-8. | ||||
Ref 531828 | Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature. 2012 Feb 29;483(7388):213-7. | ||||
Ref 533640 | Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science. 1995 Sep 22;269(5231):1737-40. |
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