Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01JMC
|
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| Former ID |
DCL000872
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| Drug Name |
Lorcaserin
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| Synonyms |
APD 356; APD356; AR-10A; (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine; 10-chloro-2-methyl-4-azabicyclo[5.4.0]undeca-8,10,12-triene
|
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| Drug Type |
Small molecular drug
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| Company |
Arena Pharmaceuticals Inc.
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| Structure |
|
Download2D MOL |
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| Formula |
C11H14ClN
|
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| InChI |
InChI=1S/C11H14ClN/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9/h2-3,6,8,13H,4-5,7H2,1H3/t8-/m0/s1
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| InChIKey |
XTTZERNUQAFMOF-QMMMGPOBSA-N
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| CAS Number |
CAS 616202-92-7
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| PubChem Compound ID | |||||
| PubChem Substance ID |
16769280, 23759570, 50076564, 56405331, 80942818, 81044375, 92719328, 93309628, 103443775, 104047951, 124894047, 126620900, 126651854, 126665802, 132608831, 135261408, 135650530, 135723896, 135727785, 137001355, 140812879, 144206569, 160644926, 160827934, 163093396, 163391282, 163620732, 163686045, 164228304, 164761636, 170466882, 170524167, 172087023, 175268181, 184816814, 198993060, 204431113, 223399569, 223565951, 223676318, 224280758, 226531083, 247440081, 249582104, 252438298
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| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 2C receptor | Target Info | Agonist | [536710], [550266] | |
| PANTHER Pathway | 5HT2 type receptor mediated signaling pathway | ||||
| References | |||||
| Ref 532210 | Nat Rev Drug Discov. 2013 Feb;12(2):87-90. | ||||
| Ref 536710 | Anti-obesity drugs. Expert Opin Pharmacother. 2008 Jun;9(8):1339-50. | ||||
| Ref 539956 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2941). | ||||
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