Drug Information

Drug General Information
Drug ID
D01MHI
Former ID
DIB009980
Drug Name
Coluracetam
Synonyms
BCI-540; MKC-231; High-affinity choline uptake facilitator (CNS disorders), Mitsubishi; Neurons growth promoting compound (major depressive disorder/anxiety), BrainCells; High-affinity choline uptake facilitator (depression/ anxiety), BrainCells
Drug Type
Small molecular drug
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Phase 2 [522235]
Company
Mitsubishi Pharma Corp
Structure
Download
2D MOL

3D MOL
Formula
C19H23N3O3
Canonical SMILES
c12c(nc3c(c1NC(=O)CN1C(=O)CCC1)CCCC3)oc(c2C)C
CAS Number
CAS 135463-81-9
PubChem Compound ID
214346
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Modulator [529446]
References
Ref 522235ClinicalTrials.gov (NCT00621270) Safety and Effectiveness Study of BCI-540 Versus Placebo in the Treatment of Major Depressive Disorder With Concomitant Anxiety. U.S. National Institutes of Health.
Ref 529446MKC-231, a choline uptake enhancer: (2) Effect on synthesis and release of acetylcholine in AF64A-treated rats. J Neural Transm. 2008 Jul;115(7):1027-35.

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