Drug Information
Drug General Information | |||||
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Drug ID |
D01OHD
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Former ID |
DIB003006
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Drug Name |
AMXT-1501
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Synonyms |
Difluoromethylornithine + polyamine transport inhibitors (head and neck cancer), Aminex Therapeutics; Polyamine transport inhibitors + polyamine biosynthesis inhibitor (head and neck cancer), Aminex Therapeutics/MediQuest Therapeutics; MQT-1426 + DFMO (head and neck cancer), Aminex Therapeutics/MediQuest Therapeutics; Polyamine-based therapy (head and neck-squamous cell carcinoma), Aminex Therapeutics/MediQuest Therapeutics
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Indication | Head and neck cancer [ICD9: 140-149, 140-229; ICD10:C07-C14, C32-C33] | Investigative | [543400] | ||
Company |
MediQuest Therapeutics Inc
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Target and Pathway | |||||
Target(s) | Ornithine decarboxylase | Target Info | Inhibitor | [543400] | |
BioCyc Pathway | Putrescine biosynthesis I | ||||
PANTHER Pathway | Ornithine degradation | ||||
CCKR signaling map ST | |||||
Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | ||||
PathWhiz Pathway | Spermidine and Spermine Biosynthesis | ||||
References |
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