Drug Information
Drug General Information | |||||
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Drug ID |
D01PLN
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Former ID |
DAP000155
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Drug Name |
Cefalotin
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Synonyms |
Cefalothin; Cefalotina; Cefalotine; Cefalotinum; Cemastin; Cephalothin; Cephalothinum; Cephalotin; Coaxin; Keflin; Seffin; Cefalotina fabra; Cephalothin Monosodium Salt; Averon-1; Cefalotin (BAN); Cefalotina [INN-Spanish]; Cefalotina fabra (TN); Cefalotine [INN-French]; Cefalotinum [INN-Latin]; Keflin (TN); (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 3-(Acetoxymethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid; 3-(Hydroxymethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid acetate; 3-ACETOXYMETHYL-8-OXO-7-(2-THIOPHEN-2-YL-ACETYLAMINO)-5-THIA-1-AZA-BICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID; 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-, acetate (ester); 6R-trans-3-((Acetyloxy)methyl)-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-carboxylic acid; 7-(2-(2-Thienyl)acetylamido)cephalosporanic acid; 7-(2-Thienylacetamido)cephalosporanic acid; 7-(Thiophene-2-acetamido)cephalosporanic acid; 7-(Thiophene-2-acetamido)cephalosporin; 7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid
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Drug Type |
Small molecular drug
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Indication | Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] | Approved | [549818] | ||
Therapeutic Class |
Antibiotics
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Company |
Eli Lilly
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Structure |
Download2D MOL |
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Formula |
C16H16N2O6S2
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Canonical SMILES |
CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)O
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InChI |
1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1
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InChIKey |
XIURVHNZVLADCM-IUODEOHRSA-N
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CAS Number |
CAS 153-61-7
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PubChem Compound ID | |||||
PubChem Substance ID |
9963, 602881, 824703, 7886646, 7978894, 8153752, 11335272, 11360511, 11362964, 11365526, 11368088, 11371283, 11373877, 11376250, 11461483, 11466747, 11467867, 11483898, 11486594, 11487937, 11490148, 11492084, 11493924, 14781066, 16794138, 29215241, 29225038, 46509079, 47193756, 47588840, 47662113, 47736307, 47810601, 47885259, 48110301, 48334326, 48334327, 48415743, 50050997, 50716459, 51091939, 57323124, 81093187, 84981763, 85788476, 87322650, 103186843, 104097230, 104310899, 124766006
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ChEBI ID |
ChEBI:50895
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SuperDrug ATC ID |
J01DB03
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SuperDrug CAS ID |
cas=000153617
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Target and Pathway | |||||
Target(s) | D-alanyl-D-alanine carboxypeptidase | Target Info | Inhibitor | [537844] | |
References |
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