Drug Information
Drug General Information | |||||
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Drug ID |
D01REJ
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Former ID |
DIB009063
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Drug Name |
VBY- 891
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Synonyms |
VBY-891
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Indication | Autoimmune diabetes [ICD10:E08-E13] | Phase 1 | [1] | ||
Company |
Virobay Inc
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Target and Pathway | |||||
Target(s) | Cathepsin S | Target Info | Modulator | [2] | |
KEGG Pathway | Lysosome | ||||
Phagosome | |||||
Antigen processing and presentation | |||||
Tuberculosis | |||||
NetPath Pathway | Leptin Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
Reactome | Endosomal/Vacuolar pathway | ||||
Degradation of the extracellular matrix | |||||
Trafficking and processing of endosomal TLR | |||||
Assembly of collagen fibrils and other multimeric structures | |||||
MHC class II antigen presentation | |||||
WikiPathways | Class I MHC mediated antigen processing & presentation | ||||
Trafficking and processing of endosomal TLR | |||||
References | |||||
REF 1 | ClinicalTrials.gov (NCT01947738) Safety Study of VBY-891 in Healthy Volunteers After Single or Multiple (7 Days) of Oral Dosing (VBY891P1). U.S. National Institutes of Health. | ||||
REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2353). | ||||
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