Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01XDL
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| Former ID |
DAP000050
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| Drug Name |
Idarubicin
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| Synonyms |
DMDR; Idamycin; Idarubicina; Idarubicine; Idarubicinum; Zavedos; Idarubicin Hcl; Idarubicin Hcl Pfs; Idarubicin hydrochloride; DM5; I 1656; IMI 30; IMI-30; Idamycin (TN); Idarubicin (INN); Idarubicin [INN:BAN]; Idarubicina [INN-Spanish]; Idarubicine [INN-French]; Idarubicinum [INN-Latin]; Zavedos (TN); (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside; (1s,3s)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-A-l-lyxo-hexopyranoside; (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione; (7S-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; 4-DMD; 4-Demethoxydaunomycin; 4-Demethoxydaunorubicin; 4-Desmethoxydaunorubicin
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Anticancer Agents
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| Company |
Ben Venue Laboratories
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| Structure |
|
Download2D MOL |
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| Formula |
C26H27NO9
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| InChI |
InChI=1S/C26H27NO9/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3/t10-,15-,16-,17-,21+,26-/m0/s1
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| InChIKey |
XDXDZDZNSLXDNA-TZNDIEGXSA-N
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| CAS Number |
CAS 58957-92-9
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| PubChem Compound ID | |||||
| PubChem Substance ID |
794734, 7887077, 7979585, 8177897, 11378086, 14810780, 14908709, 17405162, 24278488, 26697284, 26704230, 26704281, 34708383, 46506973, 47959947, 48416101, 49995025, 50106402, 50106403, 50106404, 53777706, 53788391, 57312753, 79820214, 85789484, 87325144, 90340569, 92303774, 92308741, 96024754, 103311042, 104340903, 117597729, 117695696, 121361286, 124749845, 124891657, 126626724, 126661729, 127301008, 127301009, 127301010, 127301011, 127301012, 127301013, 127301014, 127301015, 127301016, 127301017, 127301018
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| ChEBI ID |
ChEBI:42068
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| SuperDrug ATC ID |
L01DB06
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| SuperDrug CAS ID |
cas=058957929
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| Target and Pathway | |||||
| Target(s) | DNA topoisomerase II | Target Info | Modulator | [556264] | |
| References | |||||
| Ref 535668 | New drugs for the treatment of cancer, 1990-2001. Isr Med Assoc J. 2002 Dec;4(12):1124-31. | ||||
| Ref 542089 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7083). | ||||
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