Drug Information

Drug General Information
Drug ID
D01XGG
Former ID
DNC010348
Drug Name
N-(7-methoxy-4-phenylbenzofuran-2-yl)acetamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530599]
Structure
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2D MOL

3D MOL
Formula
C17H15NO3
Canonical SMILES
CC(=O)NC1=CC2=C(C=CC(=C2O1)OC)C3=CC=CC=C3
InChI
1S/C17H15NO3/c1-11(19)18-16-10-14-13(12-6-4-3-5-7-12)8-9-15(20-2)17(14)21-16/h3-10H,1-2H3,(H,18,19)
InChIKey
QFMYZXFFZWTGIP-UHFFFAOYSA-N
PubChem Compound ID
46230982
Target and Pathway
Target(s) Adenosine A2a receptor Target Info Inhibitor [530599]
KEGG Pathway Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Parkinson's disease
Alcoholism
Pathway Interaction Database HIF-2-alpha transcription factor network
PathWhiz Pathway Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
Reactome NGF-independant TRKA activation
Adenosine P1 receptors
G alpha (s) signalling events
Surfactant metabolism
WikiPathways Nucleotide GPCRs
Monoamine Transport
GPCRs, Class A Rhodopsin-like
NGF signalling via TRKA from the plasma membrane
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 530599Bioorg Med Chem Lett. 2010 Feb 1;20(3):1090-3. Epub 2009 Dec 11.Synthetic studies on selective adenosine A2A receptor antagonists: synthesis and structure-activity relationships of novel benzofuran derivatives.
Ref 530599Bioorg Med Chem Lett. 2010 Feb 1;20(3):1090-3. Epub 2009 Dec 11.Synthetic studies on selective adenosine A2A receptor antagonists: synthesis and structure-activity relationships of novel benzofuran derivatives.

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