Drug General Information
Drug ID
D01ZHW
Former ID
DIB020490
Drug Name
N-arachidonoylglycine
Synonyms
NAGly
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540488]
Structure
Download
2D MOL
Formula
C22H35NO3
InChI
InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(24)23-20-22(25)26/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-15-
InChIKey
YLEARPUNMCCKMP-DOFZRALJSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) LPA5 receptor Target Info Agonist [529486]
GPR18 Target Info Agonist [528313]
References
Ref 540488(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3635).
Ref 528313Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18. Biochem Biophys Res Commun. 2006 Sep 1;347(3):827-32. Epub 2006 Jul 10.
Ref 529486Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92. J Biol Chem. 2008 Jul 25;283(30):21054-64.

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