Drug Information
Drug General Information | |||||
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Drug ID |
D02BPT
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Former ID |
DIB018359
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Drug Name |
[3H]nicotine
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
Download2D MOL |
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Formula |
C10H14N2
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InChI |
InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3
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InChIKey |
SNICXCGAKADSCV-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Neuronal acetylcholine receptor protein, beta-2 chain | Target Info | Agonist | [2] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
Cholinergic synapse | |||||
Nicotine addiction | |||||
PANTHER Pathway | Nicotinic acetylcholine receptor signaling pathway | ||||
Nicotine pharmacodynamics pathway | |||||
Reactome | Highly sodium permeable acetylcholine nicotinic receptors | ||||
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | |||||
Highly calcium permeable nicotinic acetylcholine receptors | |||||
WikiPathways | SIDS Susceptibility Pathways | ||||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
Nicotine Activity on Dopaminergic Neurons | |||||
References | |||||
REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3978). | ||||
REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 465). | ||||
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