Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02CQN
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| Former ID |
DNC011257
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| Drug Name |
5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C20H17ClN2O
|
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| Canonical SMILES |
CC1=CC=CC=C1CNC(=O)C2=CN=CC(=C2)C3=CC=C(C=C3)Cl
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| InChI |
1S/C20H17ClN2O/c1-14-4-2-3-5-16(14)13-23-20(24)18-10-17(11-22-12-18)15-6-8-19(21)9-7-15/h2-12H,13H2,1H3,(H,23,24)
|
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| InChIKey |
MLDMXXWILKZITA-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Voltage-gated sodium channel subunit alpha Nav1.8 | Target Info | Inhibitor | [1] | |
| PN3 Na+ channel | Target Info | Inhibitor | [1] | ||
| Reactome | Interaction between L1 and Ankyrins | ||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2010 Nov 15;20(22):6812-5. Epub 2010 Sep 18.Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. | ||||
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