Drug General Information
Drug ID	D02DTQ
Former ID	DIB016648
Drug Name	PF-3893787
Synonyms	PF-03893787; PF-3826719
Drug Type	Small molecular drug
Indication	Asthma [ICD10:J45]		Phase 1	[531625]
Company	Pfizer Inc
Structure		Download 2D MOL 3D MOL
Formula	C13H22N6
Canonical SMILES	c1(nc(cc(n1)N1C[C@@H](CC1)NC)NCC1CC1)N
PubChem Compound ID	24745335
Target and Pathway
Target(s)	Histamine H4 receptor	Target Info	Antagonist	[531625]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 531625	Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6596-602.
Ref 531625	Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6596-602.

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