Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02EVT
|
||||
| Former ID |
DIB001029
|
||||
| Drug Name |
SAR-152954
|
||||
| Synonyms |
Histamine H3 antagonist (sleep disorder), Sanofi-aventis
|
||||
| Indication | Sleep disorders [ICD9: 307.4, 327, 780.5; ICD10:F51, G47] | Discontinued in Phase 1 | [1] | ||
| Company |
Sanofi
|
||||
| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | Antagonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033674) | ||||
| REF 2 | Clinical pipeline report, company report or official report of Sanofi. | ||||
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