Drug Information

Drug General Information
Drug ID
D02HWL
Former ID
DIB020602
Drug Name
oleoyl-lysophosphatidylcholine
Synonyms
lysolecithin; LPC 18:1; lysophosphatidylcholine(18:1); OLPC
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540484]
Structure
Download
2D MOL
Formula
C26H52NO7P
InChI
InChI=1S/C26H52NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h12-13,25,28H,5-11,14-24H2,1-4H3/b13-12-/t25-/m1/s1
InChIKey
YAMUFBLWGFFICM-PTGWMXDISA-N
PubChem Compound ID
16081932
PubChem Substance ID
7983928, 24727804, 24896294, 28692103, 29965174, 57379824, 57392125, 126524654, 137324604, 138820943, 162227243, 164174758, 178100540, 179660971, 194159168, 208265606, 223438381, 241326269, 250133141
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [527346]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 540484(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3623).
Ref 527346Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor. Biochem Biophys Res Commun. 2005 Jan 28;326(4):744-51.

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