Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02KAF
|
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| Former ID |
DIB011815
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| Drug Name |
GT-2203
|
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| Synonyms |
GT-2144; GT-2203; GT-2204; GT-2223; GT-2328; GT-2396; GT-2397; GT-2431; H3 agonists, Gliatech
|
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| Indication | Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] | Terminated | [1] | ||
| Company |
Gliatech Inc
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
[C@H]1(C[C@H]1N)c1nc[nH]c1
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| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008938) | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264). | ||||
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