Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D02KAF
|
||||
Former ID |
DIB011815
|
||||
Drug Name |
GT-2203
|
||||
Synonyms |
GT-2144; GT-2203; GT-2204; GT-2223; GT-2328; GT-2396; GT-2397; GT-2431; H3 agonists, Gliatech
|
||||
Indication | Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] | Terminated | [1] | ||
Company |
Gliatech Inc
|
||||
Structure |
![]() |
Download2D MOL |
|||
Canonical SMILES |
[C@H]1(C[C@H]1N)c1nc[nH]c1
|
||||
Target and Pathway | |||||
Target(s) | Histamine H3 receptor | Target Info | Agonist | [2] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
Reactome | Histamine receptors | ||||
G alpha (i) signalling events | |||||
WikiPathways | Monoamine Transport | ||||
GPCRs, Class A Rhodopsin-like | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
References | |||||
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008938) | ||||
REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264). | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.