TTD | Drug: D02OAI

Drug General Information
Drug ID	D02OAI
Former ID	DIB018782
Drug Name	AGN193836
Synonyms	AGN-193836; AGN 193836
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539715]
Structure		Download 2D MOL
Formula	C22H22BrF2NO4
InChI	InChI=1S/C22H22BrF2NO4/c1-21(2)5-6-22(3,4)16-11(21)9-14(18(27)17(16)23)26-19(28)10-7-12(24)15(20(29)30)13(25)8-10/h7-9,27H,5-6H2,1-4H3,(H,26,28)(H,29,30)
InChIKey	FADQHUSDAKOWFT-UHFFFAOYSA-N
PubChem Compound ID	23001780
PubChem Substance ID	127816690, 135649904, 232804859
Target and Pathway
Target(s)	Retinoic acid receptor alpha	Target Info	Agonist	[526437]
KEGG Pathway	Pathways in cancer
	Transcriptional misregulation in cancer
	Acute myeloid leukemia
Pathway Interaction Database	Retinoic acid receptors-mediated signaling
Reactome	Nuclear Receptor transcription pathway
WikiPathways	Vitamin A and Carotenoid Metabolism
	Nuclear Receptors in Lipid Metabolism and Toxicity
	Integrated Pancreatic Cancer Pathway
	Adipogenesis
	Nuclear Receptors
References
Ref 539715	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2649).
Ref 526437	Bioorg Med Chem Lett. 2002 Nov 4;12(21):3145-8.Synthesis and biological activity of retinoic acid receptor-alpha specific amides.

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Drug Information