Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02OYL
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| Former ID |
DNC010890
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| Drug Name |
1-(biphenyl-4-yl)-3-(4-(piperidin-1-yl)butyl)urea
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [530912] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C22H29N3O
|
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| Canonical SMILES |
C1CCN(CC1)CCCCNC(=O)NC2=CC=C(C=C2)C3=CC=CC=C3
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| InChI |
1S/C22H29N3O/c26-22(23-15-5-8-18-25-16-6-2-7-17-25)24-21-13-11-20(12-14-21)19-9-3-1-4-10-19/h1,3-4,9-14H,2,5-8,15-18H2,(H2,23,24,26)
|
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| InChIKey |
MUIUUGJVKFYPIF-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine receptor 3A | Target Info | Inhibitor | [530912] | |
| KEGG Pathway | Serotonergic synapse | ||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | 5HT3 type receptor mediated signaling pathway | ||||
| Reactome | Ligand-gated ion channel transport | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Iron uptake and transport | |||||
| References | |||||
| Ref 530912 | J Med Chem. 2010 Jun 10;53(11):4379-89.Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914). | ||||
| Ref 530912 | J Med Chem. 2010 Jun 10;53(11):4379-89.Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914). | ||||
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