TTD | Drug: D02RRY

Drug General Information
Drug ID	D02RRY
Former ID	DIB018969
Drug Name	BI6015
Synonyms	BI 6015; BI-6015
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541800]
Structure		Download 2D MOL
Formula	C15H13N3O4S
InChI	InChI=1S/C15H13N3O4S/c1-10-7-8-12(18(19)20)9-15(10)23(21,22)17-11(2)16-13-5-3-4-6-14(13)17/h3-9H,1-2H3
InChIKey	ILVCPQPMRPHZSG-UHFFFAOYSA-N
PubChem Compound ID	3269393
PubChem Substance ID	4305501, 9250917, 34643400, 48294592, 72035629, 76807887, 93321380, 106832750, 111873415, 118687072, 143901364, 164058091, 166708326, 170474672, 178103306, 196373099, 229483309, 246108201, 252158239, 252160588
Target and Pathway
Target(s)	Hepatocyte nuclear factor 4-alpha	Target Info	Antagonist	[531980]
KEGG Pathway	AMPK signaling pathway
KEGG Pathway	Maturity onset diabetes of the young
Pathway Interaction Database	Regulation of nuclear SMAD2/3 signaling
	FOXA2 and FOXA3 transcription factor networks
	HIF-1-alpha transcription factor network
Reactome	Nuclear Receptor transcription pathway
WikiPathways	Mesodermal Commitment Pathway
	Integrated Pancreatic Cancer Pathway
	Nuclear Receptors
	AMPK Signaling
References
Ref 541800	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6695).
Ref 531980	HNF4alpha antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem Biol. 2012 Jul 27;19(7):806-18.

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Drug Information