Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02RTS
|
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| Former ID |
DIB019149
|
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| Drug Name |
citric acid
|
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| Synonyms |
citrate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C6H8O7
|
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| InChI |
InChI=1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
|
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| InChIKey |
KRKNYBCHXYNGOX-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
3458, 89571, 493004, 583624, 583626, 583628, 583666, 583709, 583750, 583782, 583785, 583920, 583952, 583961, 583962, 583990, 584046, 584048, 584050, 584052, 584054, 584057, 584096, 584098, 584199, 584208, 584526, 584546, 584681, 584697, 584768, 584772, 585348, 585511, 585681, 585694, 587788, 607173, 819959, 820166, 820611, 820613, 820722, 820723, 820726, 820754, 820758, 820760, 820762, 820764
|
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| Target and Pathway | |||||
| Target(s) | Transient receptor potential cation channel subfamily V member 4 | Target Info | Activator | [2] | |
| TRPP2 | Target Info | Activator | [3] | ||
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | ||||
| Reactome | TRP channels | ||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2478). | ||||
| REF 2 | Impaired pressure sensation in mice lacking TRPV4. J Biol Chem. 2003 Jun 20;278(25):22664-8. Epub 2003 Apr 13. | ||||
| REF 3 | Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12569-74. Epub 2006 Aug 4. | ||||
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