Drug General Information
Drug ID
D02TIK
Former ID
DCL000837
Drug Name
HP-184
Synonyms
Nerispirdine; Nerispirdine hydrochloride; HP 184; N-(3-fluoropyridin-4-yl)-3-methyl-N-propylindol-1-amine; N-(n-Propyl)-3-fluoro-4-pyridinyl-1H-3-methylindol-1-amine hydrochloride; N-(3-Fluoro-4-pyridinyl)-3-methyl-N-propyl-1H-indol-1-amine; 1H-Indol-1-amine, N-(3-fluoro-4-pyridinyl)-3-methyl-N-propyl-, monohydrochloride
Drug Type
Small molecular drug
Indication Multiple scierosis [ICD9: 340; ICD10:G35] Phase 2 [536648]
Company
Sanofi-Aventis
Structure
Download
2D MOL

3D MOL

Formula
C17H18FN3
Canonical SMILES
CCCN(C1=C(C=NC=C1)F)N2C=C(C3=CC=CC=C32)C
InChI
1S/C17H18FN3/c1-3-10-20(17-8-9-19-11-15(17)18)21-12-13(2)14-6-4-5-7-16(14)21/h4-9,11-12H,3,10H2,1-2H3
InChIKey
BTDHTARYCBHHPJ-UHFFFAOYSA-N
CAS Number
CAS 119229-65-1
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily H member 2 Target Info Blocker [536648]
Voltage-gated sodium channel Target Info Blocker [536648]
PathWhiz Pathway Muscle/Heart Contraction
Reactome Voltage gated Potassium channels
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Potassium Channels
References
Ref 536648Emerging drugs for spinal cord injury. Expert Opin Emerg Drugs. 2008 Mar;13(1):63-80.
Ref 536648Emerging drugs for spinal cord injury. Expert Opin Emerg Drugs. 2008 Mar;13(1):63-80.

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