Drug General Information
Drug ID
D03AOP
Former ID
DNCL003435
Drug Name
DS-8500
Indication Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1] Phase 2 [524885]
Company
Daiichi Sankyo
Structure
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2D MOL

3D MOL

Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Modulator [544477]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 524885ClinicalTrials.gov (NCT02222350) Phase 2 Study of DS-8500a in Patients With Type 2 Diabetes. U.S. National Institutes of Health.
Ref 544477Addressing Unmet Medical Needs in Type 2 Diabetes: A Narrative Review of Drugs under Development. Curr Diabetes Rev. 2015 March; 11(1): 17-31.

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