Drug General Information
Drug ID
D03BGG
Former ID
DIB015691
Drug Name
ST-1141
Synonyms
Ghrelin agonist (oral, opioid-induced bowel dysfunction), Helsinn
Indication Functional bowel disorder [ICD10:K00-K93] Phase 1 [548492]
Company
Sapphire Therapeutics Inc
Target and Pathway
Target(s) Growth hormone secretagogue receptor type 1 Target Info Agonist [550985]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway Leptin Signaling Pathway
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 548492Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025998)
Ref 550985The Prokinetic Face of Ghrelin. International Journal of Peptides Volume 2010 (2010), Article ID 493614, Page(11).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.