Drug Information

Drug General Information
Drug ID
D03DHQ
Former ID
DCL000760
Drug Name
CX-516
Synonyms
Ampalex; BDP 12; CX 516; CX516; BDP-12; SPD-420; Piperidin-1-yl(quinoxalin-6-yl)methanone; 1-(6-Quinoxalinylcarbonyl)piperidine; 1-(6-quinoxalinylcarbonyl)-Piperidine; 1-(quinoxalin-6-ylcarbonyl)piperidine; 6-(piperidin-1-ylcarbonyl)quinoxaline
Drug Type
Small molecular drug
Indication Schizophrenia; Pervasive developmental disorder [ICD9: 295, 299; ICD10:F20, F84] Phase 2/3 [467505], [536120]
Company
Cortex
Structure
Download
2D MOL

3D MOL
Formula
C14H15N3O
InChI
InChI=1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2
InChIKey
ANDGGVOPIJEHOF-UHFFFAOYSA-N
CAS Number
CAS 154235-83-3
PubChem Compound ID
148184
PubChem Substance ID
586267, 10249834, 14823193, 46225133, 50014454, 50407829, 57346716, 58107168, 87245449, 92719586, 93309743, 93581252, 96021227, 99300590, 99431536, 99437665, 99452656, 103374311, 103991908, 104418433, 118845667, 123046084, 125341848, 126574412, 126628160, 126651821, 126671254, 126733033, 127430856, 134339248, 135105380, 136377903, 136946430, 137008005, 142542261, 143493398, 144115603, 145238952, 152213031, 152242353, 160815141, 162190884, 162221093, 163090027, 163620727, 163686041, 163801192, 164045281, 164187479, 164831044
SuperDrug ATC ID
P01BB02
SuperDrug CAS ID
cas=000609789
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Modulator [536120]
References
Ref 467505(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4165).
Ref 536120Autism spectrum disorders: emerging pharmacotherapy. Expert Opin Emerg Drugs. 2005 Aug;10(3):521-36.
Ref 536120Autism spectrum disorders: emerging pharmacotherapy. Expert Opin Emerg Drugs. 2005 Aug;10(3):521-36.

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