Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03JYN
|
||||
| Former ID |
DNC008483
|
||||
| Drug Name |
1-(phenyl(p-tolyl)methylene)thiosemicarbazide
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C15H15N3S
|
||||
| Canonical SMILES |
CC1=CC=C(C=C1)C(=NNC(=S)N)C2=CC=CC=C2
|
||||
| InChI |
1S/C15H15N3S/c1-11-7-9-13(10-8-11)14(17-18-15(16)19)12-5-3-2-4-6-12/h2-10H,1H3,(H3,16,18,19)/b17-14+
|
||||
| InChIKey |
DZOZYORQEZEOCT-SAPNQHFASA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cathepsin B | Target Info | Inhibitor | [1] | |
| Cathepsin L | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Lysosome | ||||
| Antigen processing and presentationhsa04142:Lysosome | |||||
| Phagosome | |||||
| Antigen processing and presentation | |||||
| Proteoglycans in cancer | |||||
| Rheumatoid arthritis | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| IL2 Signaling PathwayNetPath_16:IL4 Signaling Pathway | |||||
| TGF_beta_Receptor Signaling Pathway | |||||
| Reactome | Collagen degradation | ||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Degradation of the extracellular matrix | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2008 May 1;18(9):2883-5. Epub 2008 Apr 8.Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.