Drug Information

Drug General Information
Drug ID
D03KLO
Former ID
DNC007127
Drug Name
2,6-dimethyl-8-ethyl-1-deazapurine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528673]
Structure
Download
2D MOL

3D MOL
Formula
C10H13N3
Canonical SMILES
CCC1=NC2=C(N1)C(=CC(=N2)C)C
InChI
1S/C10H13N3/c1-4-8-12-9-6(2)5-7(3)11-10(9)13-8/h5H,4H2,1-3H3,(H,11,12,13)
InChIKey
XWWJWZJOSWSJQV-UHFFFAOYSA-N
PubChem Compound ID
9815374
Target and Pathway
Target(s) Adenosine A1 receptor Target Info Inhibitor [528673]
KEGG Pathway cGMP-PKG signaling pathway
cAMP signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
Morphine addiction
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 528673J Med Chem. 2007 Feb 22;50(4):828-34.2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists.
Ref 528673J Med Chem. 2007 Feb 22;50(4):828-34.2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.