Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03KQG
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| Former ID |
DNC012069
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| Drug Name |
Pyrrolidin-1-yl-thiourea
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C5H11N3S
|
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| Canonical SMILES |
C1CCN(C1)NC(=S)N
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| InChI |
1S/C5H11N3S/c6-5(9)7-8-3-1-2-4-8/h1-4H2,(H3,6,7,9)
|
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| InChIKey |
LUZJFNYVKQEEGM-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Vanilloid receptor | Target Info | Inhibitor | [1] | |
| Vanilloid receptor 1 | Target Info | Inhibitor | [1] | ||
| Transient receptor potential cation channel subfamily V member 4 | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Inflammatory mediator regulation of TRP channelshsa04750:Inflammatory mediator regulation of TRP channels | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
| Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
| Reactome | TRP channelsR-HSA-3295583:TRP channels | ||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2004 Apr 5;14(7):1693-6.N-4-methansulfonamidobenzyl-N'-2-substituted-4-tert-butyl-benzyl thioureas as potent vanilloid receptor antagonistic ligands. | ||||
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