Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D03RGO
|
||||
Former ID |
DIB005110
|
||||
Drug Name |
CP-331
|
||||
Synonyms |
CP-6
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Terminated | [1] | ||
Company |
Zeria Pharmaceutical Co Ltd
|
||||
Structure |
![]() |
Download2D MOL |
|||
Formula |
C38H44ClN3O6S
|
||||
Canonical SMILES |
n1(c(c(c2c1ccc(c2)OC)CC(=O)OCCSCC(=O)NCCCOc1cc(CN2CCCCC<br />2)ccc1)C)C(=O)c1ccc(cc1)Cl
|
||||
CAS Number |
CAS 127966-70-5
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Histamine H2 receptor | Target Info | Modulator | [2] | |
KEGG Pathway | Calcium signaling pathway | ||||
Neuroactive ligand-receptor interaction | |||||
Gastric acid secretion | |||||
PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Histamine H2 receptor mediated signaling pathway | |||||
PathWhiz Pathway | Intracellular Signalling Through Histamine H2 Receptor and Histamine | ||||
Gastric Acid Production | |||||
Reactome | Histamine receptors | ||||
G alpha (s) signalling events | |||||
WikiPathways | Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | |||||
Secretion of Hydrochloric Acid in Parietal Cells | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
References | |||||
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001767) | ||||
REF 2 | Conjugation of chlorin p(6) to histamine enhances its cellular uptake and phototoxicity in oral cancer cells. Cancer Chemother Pharmacol. 2011 Aug;68(2):359-69. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.