Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03RGO
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| Former ID |
DIB005110
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| Drug Name |
CP-331
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| Synonyms |
CP-6
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| Drug Type |
Small molecular drug
|
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| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Terminated | [1] | ||
| Company |
Zeria Pharmaceutical Co Ltd
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| Structure |
|
Download2D MOL |
|||
| Formula |
C38H44ClN3O6S
|
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| Canonical SMILES |
n1(c(c(c2c1ccc(c2)OC)CC(=O)OCCSCC(=O)NCCCOc1cc(CN2CCCCC<br />2)ccc1)C)C(=O)c1ccc(cc1)Cl
|
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| CAS Number |
CAS 127966-70-5
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Histamine H2 receptor | Target Info | Modulator | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gastric acid secretion | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Histamine H2 receptor mediated signaling pathway | |||||
| PathWhiz Pathway | Intracellular Signalling Through Histamine H2 Receptor and Histamine | ||||
| Gastric Acid Production | |||||
| Reactome | Histamine receptors | ||||
| G alpha (s) signalling events | |||||
| WikiPathways | Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| Secretion of Hydrochloric Acid in Parietal Cells | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001767) | ||||
| REF 2 | Conjugation of chlorin p(6) to histamine enhances its cellular uptake and phototoxicity in oral cancer cells. Cancer Chemother Pharmacol. 2011 Aug;68(2):359-69. | ||||
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