Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03RTC
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| Former ID |
DIB014140
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| Drug Name |
BMS-812204
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| Synonyms |
CB1 antagonists (obesity), BMS; CB1 antagonists (obesity), Bristol-Myers Squibb
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| Indication | Obesity [ICD9: 278; ICD10:E66] | Investigative | [1] | ||
| Company |
Bristol-Myers Squibb Co
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
FC(F)(c1nc(c(Cn2c(=O)c(c3cnc(nc3)C)c(c3n2c(=O)n(n3)CC)c<br />2ccc(cc2)Cl)cc1)C)F
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| Target and Pathway | |||||
| Target(s) | Cannabinoid receptor 1 | Target Info | Antagonist | [1] | |
| KEGG Pathway | Rap1 signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Retrograde endocannabinoid signaling | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| Pathway Interaction Database | N-cadherin signaling events | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| BDNF signaling pathway | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 56). | ||||
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