TTD | Drug: D03TSY

Drug General Information
Drug ID	D03TSY
Former ID	DIB019796
Drug Name	E55888
Synonyms	E-55888; E 55888
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540551]
Structure		Download 2D MOL
Formula	C16H23N3
InChI	InChI=1S/C16H23N3/c1-12-16(13(2)19(5)17-12)15-8-6-7-14(11-15)9-10-18(3)4/h6-8,11H,9-10H2,1-5H3
InChIKey	MFUWRMRKXKCSPL-UHFFFAOYSA-N
PubChem Compound ID	24825775
PubChem Substance ID	49847116, 57135390, 140873475, 141011740, 162221523, 178100758, 224399505, 229362632, 244740263
Target and Pathway
Target(s)	5-hydroxytryptamine 7 receptor	Target Info	Agonist	[529896]
KEGG Pathway	Ras signaling pathway
	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome	Serotonin receptors
Reactome	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 540551	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3929).
Ref 529896	5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice. Pain. 2009 Feb;141(3):239-47.

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Drug Information