Drug General Information
Drug ID
D03UID
Former ID
DNC001218
Drug Name
RJR-2403
Drug Type
Small molecular drug
Indication Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3] Discontinued in Phase 2 [540610], [546260]
Structure
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2D MOL

3D MOL

Formula
C10H14N2
InChI
InChI=1S/C10H14N2/c1-11-7-3-2-5-10-6-4-8-12-9-10/h2,4-6,8-9,11H,3,7H2,1H3/b5-2+
InChIKey
JUOSGGQXEBBCJB-GORDUTHDSA-N
CAS Number
CAS 55088-60-3
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Nicotinic acetylcholine receptor Target Info Agonist [535334]
References
Ref 540610(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3994).
Ref 546260Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007149)
Ref 535334The therapeutic potential of nicotinic acetylcholine receptor agonists for pain control. Expert Opin Investig Drugs. 2001 Oct;10(10):1819-30.

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