Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03UNN
|
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| Former ID |
DIB010602
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| Drug Name |
L-689560
|
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| Drug Type |
Small molecular drug
|
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| Indication | Neurodegenerative disease [ICD9: 330-337; ICD10:G30-G32] | Terminated | [1], [2] | ||
| Company |
Merck & Co Inc
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C17H15Cl2N3O3
|
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| InChI |
InChI=1S/C17H15Cl2N3O3/c18-9-6-11(19)15-12(7-9)21-14(16(23)24)8-13(15)22-17(25)20-10-4-2-1-3-5-10/h1-7,13-14,21H,8H2,(H,23,24)(H2,20,22,25)/t13-,14+/m1/s1
|
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| InChIKey |
UCKHICKHGAOGAP-KGLIPLIRSA-N
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| CAS Number |
CAS 139051-78-8
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | NMDA receptor | Target Info | Modulator | [3] | |
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4239). | ||||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001828) | ||||
| REF 3 | Characterization of the binding of [3H]L-689,560, an antagonist for the glycine site on the N-methyl-D-aspartate receptor, to rat brain membranes. Mol Pharmacol. 1992 May;41(5):923-30. | ||||
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